INTERNATIONAL FEDERATION OF PLACENTA ASSOCIATIONS MEETING 2023
PROGRAMME
Monday 4 September 2023
Free for 70 registrants, offsite at Te Puia
Tuesday 5 September 2023
Stafford/Dodd Room
Stafford/Dodd Room
Stafford/Dodd Room
Batten Room
1600 - 1615
Batten Room
Dawn Mark
Joan Hunt IFPA Senior Award
Prof Greg Rice (University of Queensland, Australia)
Extracellular vesicle signalling and pregnancy engineering the opportunities
Chair: Prof Claire Roberts
New Investigator Travel Award Presentations to Awardees
Batten Room
Skyline Rotorua
Wednesday 6 September 2023
Join the University of Auckland crew for a flat 6km geothermal run around Sulphur Bay. Meet in front of the Novotel Hotel.
View the route on strava
Download a pdf guide of the route here
Symposium 1 - Implantation and Early Pregnancy
Batten Room
Prof Niamh Forde (University of Leeds, UK)
Insights into endometrial function: What can we learn from species with diverse implantation strategies?Dr Margherita Turco (Friedrich Miescher Institute for Biomedical Research (FMI), Basel, Switzerland)
Organoid systems for investigating trophoblast biology and maternal-fetal interactions in human pregnancyDr Emma Lucas (University of Warwick, UK)
Endometrial fate decisions at implantation and the risk of recurrent miscarriage
Chairs: Prof Guiying Nie and Prof Gendie Lash
Elsevier Placenta New Investigator Award Presentations - Session 1
Batten Room
1100-1115: Dr Rowan Karvas (Washington University in St Louis, USA)
3D-cultured human blastoids model trophoblast expansion, diversification, and invasion during early post-implantation development
1115-1130: Matthew Shannon (BC Children's Hospital Research Institute, Canada)
Single-cell transcriptomics define a unique progenitor state in trophoblast stem cell organoids
1130-1145: Karolina Radziun (University of Liverpool, UK)
Novel 3D in vitro human placenta-on-a-chip model derived using human trophoblast stem cells differentiated towards syncytiotrophoblasts and extravillous trophoblasts to mimic both villi and implantation sides of the placenta
1145-1200: Dr Michelle Broekhuizen (Erasmus MC, Netherlands)
Flow-mediated vasodilation is impaired in placentas from women with preeclampsia
1200-1215: Julián Andrés Henao Restrepo (Jena University Hospital, Germany)
Astrocyte and microglia activation by circulating extracellular vesicles from preeclampsia exacerbates blood-brain barrier disruption on a microfluidic BBB-on-chip model
1215-1230: Robert Morey (University of California San Diego, USA)
Trajectory modelling of first trimester placenta highlight differences between cytotrophoblast progenitors and trophoblast stem cells
Chairs: Dr Padma Murthi & Prof Stephen Renaud
Hillary Room
Batten Room 1
Organisers:
Prof Terry Morgan (Oregon Health and Science University, USA)
Dr Athena Chen (Oregon Health and Science University, USA)
Aims:
1) Appreciate that placental pathology provides an autopsy of the pregnancy.
2) Learn that although placental viral infections seem to be uncommon, they are high impact.
3) Recognize that developmental programming effects of placental pathology may be common
Workshop 2: Beyond 2D - novel culture approaches to improve the way we study the placenta
Batten Room 2
Organisers:
Dr Michelle Oyen (Washington University, St Louis, USA)
Dr Samantha Zambuto (Washington University, St Louis, USA)
Aim:
The aim of this workshop is to highlight novel three-dimensional culture methods for placental modelling, including biomaterials, organoids, microfluidics, and more.
Workshop 3: Improving pregnancy health in diverse populations: a focus on placenta as a conduit
Mansfield Room
Organisers:
Prof Kirsty Pringle (University of Newcastle, Australia)
Prof Indira Mysorekar (Baylor College of Medicine, USA)
Aim:
The aim of the workshop is to understand the impact of environment and circumstance on the placenta and pregnancy outcomes and highlight the importance of including diverse populations in our research.
Workshop 4: Comparative placentation
Stafford/Dodd Room
Prof Christiane Pfarrer (University of Veterinary Medicine Hannover, Germany)
Aim:
This workshop presents a forum for those interested in aspects of placentation other than those explored in rodent models.
Batten Room
5’-tRNA fragments are syncytiotrophoblast-derived endocrine signals contributing to maternal sterile inflammation in preeclampsia
Batten Room
How to be a good mentor: what ECRs wish mentors knew
Rutherford Room
Thursday 7 September 2023
Batten Room
Why spiral arteries spiral
Chair: Prof Sally Collins
Batten Room
PAA - Batten Room 1 & 2
EPG - Stafford/Dodd RoomANZPRA - Mansfield RoomJPA - Hillary Room
Elsevier Placenta New Investigator Award Presentations - Session 2
Batten Room 1100-1115: Dr Megan Sharps (University of Manchester, UK)
Defining Higher-Order Coordination and Developmental Trajectories of Cells in First Trimester Human Placenta Following Spatial Transcriptomic Analysis
1115-1130: Camille Couture (Sainte-Justine Hospital Research Centre and Université de Montréal, Montreal, Canada)
A unique placental inflammatory profile in postpartum preeclampsia suggests an immune-driven pathology with prenatal initiation
1130-1145: Evangeline Lovell (University of Adelaide, Australia)
Maternal C1q deficiency leads to impaired decidual vascular remodelling, placental insufficiency and reduced fetal growth
1145-1200: Nikita Harvey (Memorial University of Newfoundland, Canada)
Sex differences in the impact of environmental pollutants on placental function
1200-1215: Jessica Dalton (University of Manchester, UK)
A mouse model of advanced maternal age demonstrates altered placental mitochondrial respiratory function
1215-1230: Cherlyn Tan (University of Cambridge, UK)
Alternative splicing in the transitional period underpinning the onset of maternal blood flow in the human early placenta.
Chairs: Prof Alicia Jawerbaum and Prof Hiro Nishi
IFPA ECR Session - Scientific Interviews: Dos and Don'ts
Mansfield Room
Hillary Room
Stafford/Dodd Room
Dr Gendie Lash (Guangzhou Medical University, China)
Aim:
The breadth of placental research
within Asia, and particularly in China, is rapidly expanding. In addition, the quantity and quality of
research articles from China being submitted to international journals are
rapidly increasing (this is especially true for our journal Placenta). Within
this Asian workshop, we will highlight the work of some exceptional scientists
and younger investigators in the field of maternal-fetal medicine, and discuss
the link up of Asian researchers with international collaborators in a way that
may benefit both sides.
Session Introduction:
“The state of placental research in China”
Prof Yan-Ling Wang (Chinese Academy of Sciences,
China) and Prof Gendie Lash (Guangzhou Women and Children's Medical
Centre, China)
Workshop 6: Integrated approaches to detecting pregnancy pathologies
Batten Room 1
Organisers:
Prof Sally Collins (University of Oxford, UK)
Prof Alex Heazell (University of Manchester, UK)
Workshop 7: Sex matters: differences in male and female placentas in normal and abnormal placentation
Batten Room 2
Organisers:
Prof Vicki Clifton (University of Queensland, Australia)
Dr Ashley Meakin (University of South Australia, Australia)
Aim:
To define the importance of sex specific differences in placental function and how that information can be used clinically
Mansfield Room
Organisers:
Prof Les Myatt (Oregon Health and Science University, USA)
Dr Joshua Fisher (University of Newcastle, Australia)
This workshop will discuss the role of organelles in the placenta, trophoblast function, and the development of pathologies. We aim to incite discussion on the potential to identify, treat, and prevent disease through understanding organelles.
NIH Lecture Batten Room
A/Prof Sathish Kumar (University of Wisconsin-Madison, USA) Androgens in Uteroplacental function and fetal health Chair: A/Prof Helen Jones
Posters (wine and cheese)
Rutherford Room
Optional Excursion
Redwoods Treewalk sold out.
Friday 8 September 2023
Symposium 2 - Clinical therapies for placental pregnancy disorders
Batten Room
A/Prof Lynda Harris (University
of Nebraska Medical Center, USA)
Novel Approaches to obstetric drug design and development
Prof Anna David (University College London, UK)
A journey in drug development for fetal growth restriction
A/Prof Helen Jones (University of Florida, USA)
Treating the trophoblast in fetal growth restriction
Chairs: Prof Natalie Hannan and Prof Mana Parast
Batten Room
Dr Padma Murthi (Monash University, Australia)
IFPA AGM Batten Room
Workshop 9: Placental stem cells: resolving and controlling trophoblast and stromal lineage states
Batten Room 1
Organisers:
A/Prof Jo James (University of Auckland, NZ)
Dr Francesca Soncin (UCSD, USA)
Aim:
to consider how we could improve current in vitro placental models by better defining the nature and role of placental stem cell and progenitor populations in vivo, and the impact of in vitro conditions (media/matrix) on their phenotype and differentiation capacity.
Workshop 10: Immune origins of adverse pregnancy outcomes
Batten Room 2
Organisers:
Dr Mancy Tong (Yale, USA)
Prof Indira Mysorekar (Baylor College of Medicine, USA)
Aim:
The aims of this workshop are to highlight the latest research on immune and infectious contributors to adverse pregnancy outcomes and to discuss new directions and technologies that we can utilize to push this field forward.
Workshop 11: The renaissance of placental perfusion models to understand placental transport and toxicology
Mansfield Room
Organisers:
A/Prof Christian Wadsack (University of Graz, Austria)
Dr Birgit Hirschmugl (University of Graz, Austria)
Aim:
Since the development of the ex vivo dual perfusion model of the human placenta cotyledon, the technique has provided essential insight into how nutrients, lipids, gases, immunoglobulins, endocrine agents, pharmaceuticals, chemicals, nanoparticles, micro-organisms and parasites might traverse the maternofetal barrier. Moreover, the model has been essential in gaining a better understanding of the regulation of vascular tone, endocrinology and metabolism within this organ.
In this workshop we will briefly present the advantages of the method in different fields of application. After this short introduction, we will discuss in small groups how complementary models as well as theoretical modelling might be complementary tools for a better understanding on the effect of toxic substances on the placenta and unborn.
Workshop 12: Long term impacts of pre-eclampsia/pregnancy disorders
Stafford/Dodd Room
Organisers:
Prof Larry Chamley (University of Auckland, New Zealand)
A/Prof Amanda Henry (UNSW, Australia)
Aim:
This
workshop aims to draw together the latest research on the effects of on
maternal health after a preeclamptic pregnancy, including effects on
subsequent pregnancies and long-term maternal health. We will achieve this via
short presentations followed by an audience/speaker discussion. Please come
prepared to participate.
Batten Room
Prof Ramkuman Menon (University of Texas Medical Branch at Galveston, USA) Organ-on-Chip models of feto-maternal interface to determine extracellular vesicles mediated communication during pregnancy and parturition
Prof Dave Grattan (University of Otago, NZ)
Placental lactogens act in the maternal brain to facilitate the maternal adaptation to pregnancy
Prof Kirsty Pringle (University of Newcastle, Australia)
Let's talk about RAS, baby: Interactions between the maternal and placental renin-angiotensin systems in pregnancy
Chairs: Prof Terry Morgan and Dr Sien Yee (Sandy) Lau
Te Puia
If you have any queries about the meeting arrangements, please don’t hesitate to contact us on:
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Telephone (Int): +64 360 1240
Freephone (within Aus):1800 193 405
Postal Address: PO Box 90 040 Auckland, 1142 New Zealand
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